1. Which drug name best describes the name “ibuprofen”?
A.trade name B. generic name C. brand name D.chemical name E. proprietary name
2. Which federal agency is responsible for the manufacture and distribution of controlled substances?
A.FDA B. DEA C. FTC D.ADA E. EIEIO
3. The LD50 of a drug means
A.The maximum legal dose in all fifty states
B.The dose at which 35 of 70 subjects gained the desired effect
C.The dose at which the therapeutic effect lasts 50 hours
D.The dose at which one half of the test subjects died
E.None of the above
4. Which of the following statements about drug administration is FALSE?
A.Oral administration is aided by the large surface area of the gut.
B.Oral administration is unpredictable due to individual variation.
C.IV administration bypasses absorption.
D.Drugs given orally are subject to “first pass” metabolism
E.None of the above
5. Which of the following transport process require energy to take place?
A.Simple diffusion (passive transfer) B. Facilitated diffusion C. Active transport D. two of the above E. none of the above
6. A drug that is an agonist
A.Binds to a receptor and directly alters its functioning.
B.Binds to a receptor but produces no alteration in functioning.
C.Binds to a receptor in an irreversible manner and directly alters its functioning
D.Binds to a receptor in an irreversible manner but produces no alteration in functioning
E.Binds to a receptor and produces agony.
Use the following answers for questions 7-10.
F.Toxic reaction B. Side effect C. Idiosyncratic reaction D. allergic reaction E. two of the above
7. Which of the above is an action on the target organ(s)?
8. Which of the above best describes the tendency of Benedryl to cause drowsiness?
9. Which of the above best describes anaphylaxis?
10. Which of the above would be more pronounced with an increased dose of the drug?
